PFKFB3 and cancer: According to the results, the proteins or genes HIF-1α, HK, glut1, AKT, glyceraldehyde-3-phosphate dehydrogenase, phospho-gluco dehydrogenase, ERK, ribose 5P isomerase, mTOR, glucose-6-phosphate dehydrogenase, STAT3, NF-κB, PI3K, MYC, LDH, PFK1, PFK2, transketolase and transaldolase are up regulated in cancer cells.