IKZF1 and toxic epidermal necrolysis: Also, a significant genome-wide association between CM-related SJS/TEN and IKZF1 SNPs (single nucleotide polymorphisms) were noted in the Japanese, Korean, Indian, and Thai populations with severe mucosal involvement (SMI), suggesting that IKZF1 might be a potential marker for susceptibility to CM-related SJS/TEN with SMI (Ueta et al., 2015; Chantaren et al., 2019).