AKT1 and renal cell carcinoma: lncRNA Activated in RCC with Sunitinib Resistance (lncARSR) functions as a sponge and competes for binding of miR-34 and miR-449 to their transcripts, leading to the upregulation of AXL/MET and the activation of STAT3, AKT, and ERK signaling (Qu et al., 2016).