TNF and infection: When the analysis was limited to those mice still colonized at Day 7 post-infection, the ∆lasB RP45 strain induced significantly higher levels of IL-1α, IL-1β, IL-9, IL-12p70, G-CSF, MIP-1α, MIP-1β, RANTES, and tumor necrosis factor (TNF)-α in comparison to the wt RP45 strain (Supplementary Table S1), confirming the immunomodulatory potential of LasB.