TIRAP and psoriasis: A penetratin-conjugated small peptide (TIP3) derived from the core of β-sheet region of Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP) blocks both MyD88 (myeloid-differentiation 88) and TIR-domain containing Adaptor inducing interferon-β (TRIF)-dependent TLR4 and TLR3 downstream signaling pathways and ameliorates the inflammatory symptoms in experimental psoriasis animal models (Achek et al., 2020[3]).