DHCR7-DT and rheumatoid arthritis: It is worth mentioning that based on imputation of genomics data it has been suggested by others that in addition to the 5 residues 70–74 in the TAHR that determine the SE-associated RA disease risk, peptide-binding groove residues 11 and 13 associate significantly with RA risk as well70, indirectly suggesting that AP may be involved.