The increase in GC induced by moderate stressors enhances the memory of stress-associated events [26–31] whilst a dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and functional alterations of the glucocorticoid receptor (GR) have been consistently related to PTSD-like memory impairments [7, 32, 33]. Here, NR3C1 is linked to memory impairment.