Similarly, our current immunobiological data confirmed that neutrophil recruitment was clearly evident during the early immune responses to AP, as a result of the high expression of chemokines (Cxcl15, Ccl1, 3, 4, 9, 11, 22, 24) and inflammatory cytokines (Tnf, Il3,4,5,7,13,11,16,17α,17β). This evidence concerns the gene TNF and alkaline phosphatase measurement.