The authors of that study concluded that the CXCL9, CXCL10 and CXCR3 expression induced by IFNγ in M1 macrophages causes the expression of inflammatory cytokines including IL-1β, IL-6 and TNFα and results in the progression of tissue destruction in various disorders such as metabolic diseases, asthma, allergies, atherosclerosis, fibrosis, reduced wound healing, and autoimmunity50. Here, CXCR3 is linked to metabolic disease.