In prion disease, results from our lab and others have confirmed deposition of disease-associated PrP (PrPSc) in human, bovine, primate, ovine, cervid, and rodent retina by RT-QuIC, western blot and/or immunohistochemistry [5, 20, 21, 23, 24, 29, 41, 52, 54, 55, 58, 60]. The gene discussed is PRNP; the disease is prion disease.