Among the 36 upregulated RNAs in melanoma stem cells, TPPP3 (tubulin polymerization promoting protein family member 3) [24], DOCK2 (dedicator of cytokinesis 2) [25], EIF3H (eukaryotic translation initiation factor 3 subunit H) [26], RNF128 (ring finger protein 128) [27], and DAPK1 (death-associated protein kinase 1) [28] and SYT7 (synaptotagmin 7) [29] were reported to be associated with apoptosis. The gene discussed is DOCK2; the disease is melanoma.