CMTM6 and metastatic malignant neoplasm in the lymph nodes: In univariate analysis, Borrmann type (IV; HR = 2.164, 95% CI 1.444–3.241, P < 0.001), T stage (HR = 2.627, 95% CI 1.327–4.889, P = 0.003), lymph node metastasis (HR = 2.829, 95% CI 1.475–5.424, P = 0.002), peritoneal recurrence (HR = 1.919, 95% CI 1.2633–2.914, P = 0.002), high expression of CMTM6 (HR = 1.668, 95% CI 1.032–2.695, P = 0.037), and high expression of CMTM6 combined with high expression of PD-L1 (HR = 1.757, 95% CI 1.162–2.655, P = 0.007) were associated with OS.