NPM1 and acute myeloid leukemia: However, in this study incidence of NPM1 mutation in adult AML patients was 22.7%; our findings were closer to observations from India (21%) (Chauhan et al., 2013), Egypt (21.8%) (Zidan et al., 2013), and Iran (20.8%) (Rezaei et al., 2017) and in agreement with other previous studies (Roti et al., 2006; Lin et al., 2006; Mori et al., 2007; Ahmad et al., 2009).