Extensive analysis of the transcriptional regulation of AICDA in a murine mature B-cell lymphoma cell line had revealed that CD40L, IL-4, and TGFβ induce AICDA expression via NF-κB, Stat6 and Smad3/4 signaling, respectively [32]. The gene discussed is CD40LG; the disease is B-cell non-Hodgkin lymphoma.