Higher level of EGFR expression was significantly associated with a poorer survival than compared with low expression in NSCLC patients (cutoff value of expression: 13.23; P-value: 0.017; HR: 1.3, 95% CI: 1.05–1.68), and this outcome resembled the ESR1 gene (cutoff value of expression: 7.71; P-value: 0.023; HR:1.3, 95% CI: 1.02–1.67) (Figure 7A,B). Here, ESR1 is linked to non-small cell lung carcinoma.