CRP and anemia (phenotype): In turn, EPS were independently associated with tumor location (frontal or temporal lobe, P = .013) and the following admission laboratory parameters: increased c-reactive protein (>1.0 mg/dL, P = .036) and Gamma-Glutamyl-Transferase levels (>55 U/L, P = .025), and presence of anemia (hemoglobin < 12 g/dL, P = .044/red blood cells count < 4/nL, P = .041, see also Supplementary Table S3 for the appropriate multivariate analysis).