SLC2A1 and glioma: A heterogeneous acidic environment and hypoxia conditions are fundamental for inducing glioma invasion.29 Thus, we analyzed lactate release levels in the supernatant of Glut1-KD IG27 and control IG27 glioma cells in high-(3 g/L) and low-glucose (1 g/L) glial cell medium and neuronal growth medium.