TRIM25 and acute myeloid leukemia: To clarify the mechanism of action of miR-137 in AML, we transfected Kasumi-1 cells with miR-137 inhibitors or co-transfected with si-TRIM25#1, and transfected miR-137 mimics in HL-60 cells or transfect miR-137 + TRIM25, and used qPCR to detect the efficiency of cell transfection (Figure 4a).