Also, the miR-15b-5p expression was significantly downregulated in the PD-miR-15b-5p inhibitor group, and the Akt3 expression was notably upregulated in the PD-Akt3-overexpression group, implying that the pretreatments with miR-15b-5p inhibitor and Akt3-overexpression plasmid were highly efficient. This evidence concerns the gene AKT3 and Parkinson disease.