In addition, many studies of CTCs in relation to PCa have also been reported, such as the study by El-Heliebi's group, which showed that CTCs of castration-resistant prostate cancer (CRPC) patients show positivity for androgen receptor splice variant 7 (AR-V7), androgen receptor full length (AR-FL), and PSA, which might contribute to the diagnosis or prognosis of PCa [36]. Here, KLK3 is linked to posterior cortical atrophy.