METTL3 and breast cancer: Liu performed immunohistochemical staining in 20 matched BC and adjacent normal tissues with a BC tissue microarray (TMA) and found the upregulation of WTAP (p = 0.002), KIAA1429 (p < 0.001), and RBM15 (p = 0.012) but no significant changes in METTL3, METTL14, METTL16, or RBM15B in BC specimens (Liu et al., 2019), which was different from mRNA expression.