Cui et al. (2017) reported that the knockout of METTL3 and METTL14 promoted the growth, self-renewal, and tumorigenesis of glioblastoma stem cells (GCS) partly by upregulating BRCA2. BRCA2 was tightly related to hereditary BC (Paul and Paul, 2014). The gene discussed is BRCA2; the disease is glioblastoma.