CFI and age-related macular degeneration: Menon et al. (2019) found that within the retina, the majority of genes surrounding the 34 risk loci were expressed in Müller glia and astrocytes, including leading AMD genes (nearest gene to lead GWAS variant) such as CFI, VEGFA, TIMP3, and COL4A3. They also identified the cell types within the retina that are most predictive of AMD risk are cone photoreceptors, glial, and vascular cells.