RUNX2 and retinitis pigmentosa 1: Moreover, we demonstrated for the first time that hRIFs can form CaP deposits under osteogenic conditions and that MALAT1, a highly upregulated lncRNA in RP, promotes Runt-related transcription factor 2 (Runx2) expression to regulate osteogenic differentiation of hRIFs by sponging miRNA-320a-5p.