The results demonstrated that high expressions of GNGT1 (HR = 1.17 (1.03–1.33), logrank P = 0.017), GNG4 (HR = 1.42 (1.2–1.67), logrank P = 4.4e − 05), NMU (HR = 1.48 (1.3–1.68), logrank P = 2.5e − 09), GCG (HR = 1.15 (1.01–1.31), logrank P = 0.031), TAC1 (HR = 1.23 (1.08–1.39), logrank P = 0.0017), GAST (HR = 1.27 (1.12–1.44), logrank P = 0.00025), GCGR (HR = 0.79 (0.69–0.89), logrank P = 0.00022), and NPSR1 (HR = 1.21 (1.02–1.42), logrank P = 0.024) were associated with worse overall survival for NSCLC patients (Figure 3). Here, GCG is linked to non-small cell lung carcinoma.