MMP9 and neoplasm: The results showed that IL-2, IL-12, IL-17, TNF-α, and INF-Υ, which were immunity promoting cytokines, were significantly upregulated in drug serum, while IL-10, TGF-β, VEGF, and MMP-9, which were immunity abating or tumor promoting proteins, were significantly downregulated in drug serum (Figure 7).