VEGFA and neoplasm: In order to confirm the effects of JDX on the immunological environment, the mouse drug serum produced by the gavage of JDX was detected for the expression of several immunity affecting factors including (1) the immunity promoting cytokines such as IL-2, IL-4, IL-6, IL-12, IL-17, TNF-α, and INF-Υ and (2) the immunity abating or tumor promoting proteins such as IL-10, TGF-β, VEGF, and MMP-9.