Wang et al. [66] reported that BMSCs transduced with pAd5-CMV-CYP2E1 recombinant adenovirus can act as an intermediate carrier to promote the killing effect of bystanders on melanoma cells in vitro and suppress the growth of cancer cells by activating 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide in an established mouse model of human melanoma. Here, CYP2E1 is linked to melanoma.