In the GEPIA2 analysis, the KM plotter analyses showed that the upregulated mRNA levels of TOP2A, PRC1, RACGAP1, AURKA, NUSAP1, CDCA5, ASPM, and NCAPG were correlated with worse OS in HCC patients; however, there was no significant correlation between CCNB2/CDKN3 and HCC prognosis (Figures 6A–J). This evidence concerns the gene TOP2A and hepatocellular carcinoma.