In a study of 182 stroke patients treated with intra-arterial therapies (including mechanical thrombectomy, intra-arterial tissue plasminogen activator, intra-arterial abciximab, angioplasty, and/or stenting), multivariate regression analysis of the relationship between BPV and clinical outcome showed that increased BPV predicted a worse outcome (29). The gene discussed is PLAT; the disease is stroke disorder.