GBM tissues attribute to the mesenchymal subtype and lack of epithelial feature; E-cadherin is not expressed or very low in most GBM cells (Perego et al., 2002; Utsuki et al., 2002; Lewis-Tuffin et al., 2010; Kahlert et al., 2012). Here, CDH1 is linked to glioblastoma.