In rodent seizure models and epilepsy patient post-mortem samples, some groups have found that Cx36 expression was increased (Collignon et al., 2006; Laura et al., 2015; Wu et al., 2017), while others found decreased Cx36 expression (Söhl et al., 2000; Condorelli et al., 2003) or no change (Motaghi et al., 2017). Here, GJD2 is linked to epilepsy.