Comparing our results with previously identified GWAS associations (noted in a review conducted by Kinnersley et al.20) revealed that RETREG2 (FAM134A), FAM178B and MVB12B (FAM125B) are putative novel genes implicated in glioma risk that are not also located on a known glioma risk locus and formed part of our main results. This evidence concerns the gene RETREG2 and central nervous system cancer.