We addressed the possibility that SH3GL1 could be overexpressed in T cells from RA patients and determined the expression of both SH3GL1 and the TCR molecule CD3e from whole blood of RA patients and healthy controls and found that the SH3GL1 expression correlated with expression of the CD3E molecule (Fig. 5c). This evidence concerns the gene SH3GL1 and rheumatoid arthritis.