FGFR1 and neoplasm: Unlike the parent molecule, however, p700 exhibits a broader binding specificity for other growth factor receptors such as VEGFR1, VEGFR3, PDGFRα, FGFR1, FDFR2α, FDFR3 and FDFR4, all of which are highly expressed in tumours or tumour vasculature [11].