Amongst those genes is the bone morphogenetic protein receptor type 2 gene (BMPR2), a member of the transforming growth factor-β (TGF‐β) superfamily, which mutations are recognized in around 70–80% of families with PAH and 10–20% of idiopathic PAH [13,14,15]. Here, BMPR2 is linked to pulmonary arterial hypertension.