ANGPT1 and pulmonary arterial hypertension: Blocking of the interaction between Ang1 ligand and Tie2 receptor in the lungs prevented PAH after pulmonary arterial injection of AAV containing an extracellular fragment of the Tie2 receptor (AAV-sTie2) both in MCT‐challenged rats and in rats injected with AAV‐Ang‐1 [279].