BRCA1 and breast cancer: Finally, a study conducted in the Bulgarian population of breast cancer patients with a positive family history for BRCA1 and BRCA2 SNPs identified a SNP in the 3′-UTR of BRCA2 exon 27, the mononucleotide deletion in the 5′-UTR of BRCA2 exon 27, and a mononucleotide deletion in the 3′ region downstream of the gene, all three of which are unique population SNPs and could alter transcription or translation of the protein [65].