Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) and also urothelial carcinoma-associated 1 (UCA1) have been further investigated in a cohort of independent patients, confirming the over-expression of both lncRNA in later stage of metastatic melanomas compared to primary tumors, suggesting a putative role of these lncRNAs in promoting metastasis [29]. This evidence concerns the gene MALAT1 and metastatic melanoma.