BRAF and melanoma: Khaitan et al., using a RNA microarray, found 77 lncRNAs differentially expressed in the BRAF-mutated melanoma cell line (WM1552C) compared to melanocytes, and identified Sprouty RTK Signaling Antagonist 4-Intronic Transcript 1 (SPRY4-IT1), involved in melanoma pathogenesis (see Section 5) [14].