In another clinical study 43 patients with end stage renal disease (ESRD) were separated into either the control group or the inflamed group based on their plasma C-reactive protein (CRP) levels; a control (CRP < 3.0 mg/L) and an inflamed group (CRP ≥ 3.0 mg/L) [130,132]. This evidence concerns the gene CRP and stage 5 chronic kidney disease.