We identified the top 10 variables enriched in BC as carrying, respectively 6.2% (Vδ2+ γδ KIR2DL1/DS1+), 6.1% (αβCD8+ KIR2DL1/DS1+), 4.5% (Vδ2+ γδ KIR2DL2/DL3+), 4.2% (αβCD8+ LEM), 4% (Vδ2+ γδ TEMRA, αβCD4+ conventional EEM, Vδ2+ γδ LEM), 3.7% (αβCD8+ TEMRA), 3.5% (αβCD8+ LAG3+) and 3.2% (NK CD8+) of contribution to the discrimination of groups (Figure 1C, waterfall plots, red arrow enriched in BC). The gene discussed is LAG3; the disease is breast cancer.