NCAM1 and breast cancer: Moreover, the t-SNE analysis revealed that cytotoxic TEMRA Vδ2+ γδ T cells that are enriched in BC N+ patients also display the positive expression of CD16 and CD56 proteins, which has been associated with enhanced Th1 function and tumor-induced degranulation capacity by Vδ2+ γδ T cells, comforting their highly cytotoxic and pro-inflammatory potential towards tumor cells [54,55].