LDHA and infection: Our data showed that infection is associated with enrichment in gene expression of LDHA (production of L-lactate in the host cell) and SLC16A4/MCT4 (export of L-lactate from the host cell) in HsEAS and HsAFR (Figure 3A,B and Supplementary Figures S4–S6), and with a significant decrease of L-lactate concentration in the extracellular culture medium of the infected settings (Figure 3C).