CXCL10, CCL13, SAA1, and CCL27 were more highly expressed in elderly, high‐grade, 1p19q non‐codel, IDH‐wildtype glioma patients, while SSTR5, CCL21, and HTR1A expressions were low in these malignant clinicopathological features of gliomas. Here, SAA1 is linked to central nervous system cancer.