IDUA and Scheie syndrome: Another estimate of the birth prevalence of MPS inBrazil, based on the frequency of heterozygotes for the most common pathogenicvariant of the IDUA gene (p.Trp402Ter) in healthy blood donors andon the relative frequency of homozygosity for such variant in MPS I patients (Federhen et al., 2020) wasreported as 4.62/100,000 live births, nearly three times higher than the one foundin this study (1.57).