Elevated expression of the oncogenic transcription factor c‐MYC (hereafter referred to as MYC) is a hallmark of cancer (Gabay et al, 2014) and is largely established by the formation of numerous tumor‐specific enhancers in the gene desert surrounding MYC (Ahmadiyeh et al, 2010; Chapuy et al, 2013; Hnisz et al, 2013; Herranz et al, 2014; Fulco et al, 2016; Zhang et al, 2016; Dave et al, 2017). The gene discussed is MYC; the disease is cancer.