Recent work applying network analyses to functional and structural connectomic data derived from gliomas have shown: (i) patterns of altered global connectivity depend on tumour grade in newly diagnosed glioma patients, (ii) lowered network efficiency correlates with cognitive performance in IDH1 wildtype astrocytoma and (iii) preoperative connectometry improves the prognostic value of DTI in the context of high-grade gliomas (Liu et al., 2016; Derks et al., 2017; Kesler et al., 2017). The gene discussed is IDH1; the disease is central nervous system cancer.