From the enrichment analysis, besides expression of genes involved in actin cytoskeleton organization, macrophage, endothelial cell (Figure 7C), cisplatin also downregulates expression of genes related to ECM organization, filopodium, and vascular endothelial growth factor receptor (VEGF) signaling pathway in cisplatin treated breast cancer cells, as compared to paclitaxel treatment (Figure S7A). This evidence concerns the gene VEGFA and breast cancer.