TSPO in gliomas can be non-invasively assessed with the second generation PET tracer, N,N-diethyl-2-(2-(4-(2-[18F]fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide([18F]DPA-714) 21. This evidence concerns the gene TSPO and central nervous system cancer.