(3) to determine whether captopril—a commonly prescribed angiotensin converting enzyme (ACE) inhibitor for the treatment of hypertension—which was shown to provide improvement in some of the post-radiation neuropathological and hematological side effects in mice (brain microhemorrhages, hematopoietic injuries)41—might also have some modifying effects when administered to larger mammalian brains. Here, ACE is linked to hypertensive disorder.