TWIST1 and cancer: In particular, high expression of pro-EMT transcription factors/mesenchymal markers such as N-cadherin, Twist1, ZEB-1, Vimentin, etc., and diminished expression of epithelial markers/cell adhesion molecules E-cadherin, Occludin, cytokeratin, and ZO-1 are frequently observed in many cancers undergoing EMT14.