TBX20 and myocardial infarction: Overexpression of Tbx20 in adult mouse cardiomyocytes can promote cell proliferation and significantly improve heart repair after MI.119–121 Besides, Tbx20 participated in the signaling cascade of Tbx20-PROK2-PROKR1 and regulated angiogenesis.122 The above findings provide further mechanistic insights into the link between cardiomyocyte proliferation and cardiac regeneration.