ERBB2 and breast cancer: Focusing on the Neu mouse model, since it better represents the most common etiology of the human disease2–4, we collected mammary tumors from Ganetespib-resistant and control mice at two different timepoints after the last Ganetespib dose (3 h and 24 h) and assessed the expression levels of various HSPs by quantitative RT-PCR (Fig. 2a–f).