We also assessed trophoblast apoptosis with 0.1 MOI of r-MRV strain after 48–72 h of infection and, we observed a significant increase in caspase 3/7 activity and percent apoptotic nuclei in placental trophoblasts (JEG-3, JAR, and HTR-8) (Fig. 2b–d). The gene discussed is CASP3; the disease is infection.