Analysis of gene expression profile in the livers of wild-type and LRP1 NPxY mutant mice showed higher levels of EMR1 (F4/80) mRNA in both wild-type and LRP1 NPxY mutant mice after HF feeding, but the mRNA levels of CD68 and CD11b in these animals were similar to that observed in chow-fed mice (Fig. 5B). The gene discussed is ITGAM; the disease is hydrops fetalis.